Interleukin-17 receptor E-like protein (IL17REL)
Homo sapiens — UniProt Q6ZVW7
Data last refreshed: (UniProt release unknown)
Key facts
Interleukin-17 receptor E-like protein (IL17REL) is a protein from Homo sapiens identified by UniProt accession Q6ZVW7, 507 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q6ZVW7; gene symbol IL17REL.
- Organism: Homo sapiens.
- Length: 507 amino acids.
- Top disease associations (Open Targets): ulcerative colitis, inflammatory bowel disease and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Interleukin-17 receptor E-like protein |
|---|---|
| UniProt accession | Q6ZVW7 |
| Gene | IL17REL |
| Organism | Homo sapiens |
| Length | 507 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- ulcerative colitis · score 0.37
- inflammatory bowel disease · score 0.36
- sex hormone-binding globulin measurement · score 0.32
- type 2 diabetes mellitus · score 0.26
- alkaline phosphatase measurement · score 0.22
- lymphatic system disease · score 0.17
- Barrett's esophagus · score 0.06
- head and neck squamous cell carcinoma · score 0.05
- inflammatory skin disease · score 0.04
- eosinophil percentage of leukocytes · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZVW7-F1 | alphafold | PREDICTED | 79.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZVW7.
Amino-acid sequence (507 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IL17REL?
The strongest Open Targets associations for IL17REL are ulcerative colitis, inflammatory bowel disease, sex hormone-binding globulin measurement, type 2 diabetes mellitus and alkaline phosphatase measurement.
How long is the IL17REL protein?
The Homo sapiens IL17REL protein (UniProt Q6ZVW7) is 507 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZVW7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZVW7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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