F-box only protein 50 (NCCRP1)
Homo sapiens — UniProt Q6ZVX7
Data last refreshed: (UniProt release unknown)
Key facts
F-box only protein 50 (NCCRP1) is a protein from Homo sapiens identified by UniProt accession Q6ZVX7, 275 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q6ZVX7; gene symbol NCCRP1.
- Organism: Homo sapiens.
- Length: 275 amino acids.
- Top disease associations (Open Targets): esophageal squamous cell carcinoma, triple-negative breast cancer and gonorrhea.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box only protein 50 |
|---|---|
| UniProt accession | Q6ZVX7 |
| Gene | NCCRP1 |
| Organism | Homo sapiens |
| Length | 275 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- esophageal squamous cell carcinoma · score 0.05
- triple-negative breast cancer · score 0.04
- gonorrhea · score 0.03
- Barrett's esophagus · score 0.02
- neoplasm · score 0.02
- cancer · score 0.01
- psoriasis · score 0.01
- prostate carcinoma · score 0.01
- bacterial disease · score 0.01
- infection · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZVX7-F1 | alphafold | PREDICTED | 85.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZVX7.
Amino-acid sequence (275 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NCCRP1?
The strongest Open Targets associations for NCCRP1 are esophageal squamous cell carcinoma, triple-negative breast cancer, gonorrhea, Barrett's esophagus and neoplasm.
How long is the NCCRP1 protein?
The Homo sapiens NCCRP1 protein (UniProt Q6ZVX7) is 275 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZVX7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZVX7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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