Membrane progestin receptor epsilon (PAQR9)
Homo sapiens — UniProt Q6ZVX9
Data last refreshed: (UniProt release unknown)
Key facts
Membrane progestin receptor epsilon (PAQR9) is a protein from Homo sapiens identified by UniProt accession Q6ZVX9, 377 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q6ZVX9; gene symbol PAQR9.
- Organism: Homo sapiens.
- Length: 377 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, triglyceride measurement and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Membrane progestin receptor epsilon |
|---|---|
| UniProt accession | Q6ZVX9 |
| Gene | PAQR9 |
| Organism | Homo sapiens |
| Length | 377 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- triglyceride measurement · score 0.44
- Red cell distribution width · score 0.42
- low density lipoprotein cholesterol measurement · score 0.40
- serum alanine aminotransferase measurement · score 0.39
- phosphatidylinositol measurement · score 0.39
- total cholesterol measurement · score 0.37
- phosphatidylcholine measurement · score 0.36
- HbA1c measurement · score 0.34
- apolipoprotein B measurement · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZVX9-F1 | alphafold | PREDICTED | 85.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZVX9.
Amino-acid sequence (377 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PAQR9?
The strongest Open Targets associations for PAQR9 are neurodegenerative disease, triglyceride measurement, Red cell distribution width, low density lipoprotein cholesterol measurement and serum alanine aminotransferase measurement.
How long is the PAQR9 protein?
The Homo sapiens PAQR9 protein (UniProt Q6ZVX9) is 377 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZVX9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZVX9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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