Patched domain-containing protein 4 (PTCHD4)
Homo sapiens — UniProt Q6ZW05
Data last refreshed: (UniProt release unknown)
Key facts
Patched domain-containing protein 4 (PTCHD4) is a protein from Homo sapiens identified by UniProt accession Q6ZW05, 846 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q6ZW05; gene symbol PTCHD4.
- Organism: Homo sapiens.
- Length: 846 amino acids.
- Top disease associations (Open Targets): protein measurement, mathematical ability and smoking initiation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Patched domain-containing protein 4 |
|---|---|
| UniProt accession | Q6ZW05 |
| Gene | PTCHD4 |
| Organism | Homo sapiens |
| Length | 846 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.29
- mathematical ability · score 0.24
- smoking initiation · score 0.23
- leukocyte count · score 0.19
- neoplasm · score 0.03
- gonorrhea · score 0.02
- papillary thyroid carcinoma · score 0.01
- chronic obstructive pulmonary disease · score 0.01
- idiopathic pulmonary fibrosis · score 0.01
- hepatocellular carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZW05-F1 | alphafold | PREDICTED | 82.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZW05.
Amino-acid sequence (846 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PTCHD4?
The strongest Open Targets associations for PTCHD4 are protein measurement, mathematical ability, smoking initiation, leukocyte count and neoplasm.
How long is the PTCHD4 protein?
The Homo sapiens PTCHD4 protein (UniProt Q6ZW05) is 846 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZW05 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZW05 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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