Ankyrin repeat and SAM domain-containing protein 3 (ANKS3)
Homo sapiens — UniProt Q6ZW76
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat and SAM domain-containing protein 3 (ANKS3) is a protein from Homo sapiens identified by UniProt accession Q6ZW76, 656 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q6ZW76; gene symbol ANKS3.
- Organism: Homo sapiens.
- Length: 656 amino acids.
- Top disease associations (Open Targets): Situs inversus totalis, Short stature and pulse pressure measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat and SAM domain-containing protein 3 |
|---|---|
| UniProt accession | Q6ZW76 |
| Gene | ANKS3 |
| Organism | Homo sapiens |
| Length | 656 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- Situs inversus totalis · score 0.37
- Short stature · score 0.33
- pulse pressure measurement · score 0.24
- Non-immune hydrops fetalis · score 0.11
- appendicular lean mass · score 0.11
- serum gamma-glutamyl transferase measurement · score 0.09
- protein measurement · score 0.08
- C-C motif chemokine 3 measurement · score 0.08
- ferritin measurement · score 0.08
- systolic blood pressure · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZW76-F1 | alphafold | PREDICTED | 68.59 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZW76.
Amino-acid sequence (656 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKS3?
The strongest Open Targets associations for ANKS3 are Situs inversus totalis, Short stature, pulse pressure measurement, Non-immune hydrops fetalis and appendicular lean mass.
How long is the ANKS3 protein?
The Homo sapiens ANKS3 protein (UniProt Q6ZW76) is 656 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZW76 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZW76 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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