Syntaxin-binding protein 4 (STXBP4)
Homo sapiens — UniProt Q6ZWJ1
Data last refreshed: (UniProt release unknown)
Key facts
Syntaxin-binding protein 4 (STXBP4) is a protein from Homo sapiens identified by UniProt accession Q6ZWJ1, 553 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q6ZWJ1; gene symbol STXBP4.
- Organism: Homo sapiens.
- Length: 553 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean corpuscular volume and erythrocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Syntaxin-binding protein 4 |
|---|---|
| UniProt accession | Q6ZWJ1 |
| Gene | STXBP4 |
| Organism | Homo sapiens |
| Length | 553 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- mean corpuscular volume · score 0.46
- erythrocyte count · score 0.46
- platelet count · score 0.45
- breast carcinoma · score 0.43
- age at menarche · score 0.42
- mean corpuscular hemoglobin concentration · score 0.42
- mean corpuscular hemoglobin · score 0.40
- mean reticulocyte volume · score 0.39
- red blood cell density measurement · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZWJ1-F1 | alphafold | PREDICTED | 69.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZWJ1.
Amino-acid sequence (553 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STXBP4?
The strongest Open Targets associations for STXBP4 are neurodegenerative disease, mean corpuscular volume, erythrocyte count, platelet count and breast carcinoma.
How long is the STXBP4 protein?
The Homo sapiens STXBP4 protein (UniProt Q6ZWJ1) is 553 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZWJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZWJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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