Kielin/chordin-like protein (KCP)
Homo sapiens — UniProt Q6ZWJ8
Data last refreshed: (UniProt release unknown)
Key facts
Kielin/chordin-like protein (KCP) is a protein from Homo sapiens identified by UniProt accession Q6ZWJ8, 1568 residues long. MolForge cross-references it against 0 known binders and 83 disease associations.
- UniProt accession: Q6ZWJ8; gene symbol KCP.
- Organism: Homo sapiens.
- Length: 1568 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cardiac arrhythmia and chronic obstructive pulmonary disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kielin/chordin-like protein |
|---|---|
| UniProt accession | Q6ZWJ8 |
| Gene | KCP |
| Organism | Homo sapiens |
| Length | 1568 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (83)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.40
- cardiac arrhythmia · score 0.15
- chronic obstructive pulmonary disease · score 0.15
- systemic lupus erythematosus · score 0.13
- eosinophil count · score 0.10
- hypothyroidism · score 0.10
- connective tissue disease · score 0.09
- rheumatoid arthritis · score 0.09
- Sjogren syndrome · score 0.09
- Crohn's disease · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZWJ8-F1 | alphafold | PREDICTED | 71.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZWJ8.
Amino-acid sequence (1568 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KCP?
The strongest Open Targets associations for KCP are neurodegenerative disease, cardiac arrhythmia, chronic obstructive pulmonary disease, systemic lupus erythematosus and eosinophil count.
How long is the KCP protein?
The Homo sapiens KCP protein (UniProt Q6ZWJ8) is 1568 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZWJ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZWJ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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