Cytochrome P450 4V2 (CYP4V2)
Homo sapiens — UniProt Q6ZWL3
Data last refreshed: (UniProt release unknown)
Key facts
Cytochrome P450 4V2 (CYP4V2) is a protein from Homo sapiens identified by UniProt accession Q6ZWL3, 525 residues long. MolForge cross-references it against 0 known binders and 190 disease associations.
- UniProt accession: Q6ZWL3; gene symbol CYP4V2.
- Organism: Homo sapiens.
- Length: 525 amino acids.
- Top disease associations (Open Targets): Bietti crystalline corneoretinal dystrophy, Bietti crystalline dystrophy and retinitis pigmentosa.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytochrome P450 4V2 |
|---|---|
| UniProt accession | Q6ZWL3 |
| Gene | CYP4V2 |
| Organism | Homo sapiens |
| Length | 525 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (190)
Diseases linked to this target (Open Targets).
- Bietti crystalline corneoretinal dystrophy · score 0.80
- Bietti crystalline dystrophy · score 0.68
- retinitis pigmentosa · score 0.54
- Retinal dystrophy · score 0.54
- corneal dystrophy · score 0.19
- genetic disorder · score 0.19
- factor XI measurement · score 0.14
- blood protein measurement · score 0.14
- serum lipopolysaccharide activity · score 0.13
- venous thromboembolism · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZWL3-F1 | alphafold | PREDICTED | 90.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZWL3.
Amino-acid sequence (525 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CYP4V2?
The strongest Open Targets associations for CYP4V2 are Bietti crystalline corneoretinal dystrophy, Bietti crystalline dystrophy, retinitis pigmentosa, Retinal dystrophy and corneal dystrophy.
How long is the CYP4V2 protein?
The Homo sapiens CYP4V2 protein (UniProt Q6ZWL3) is 525 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZWL3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZWL3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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