Membrane-bound glycerophospholipid O-acyltransferase 2 (MBOAT2)
Homo sapiens — UniProt Q6ZWT7
Data last refreshed: (UniProt release unknown)
Key facts
Membrane-bound glycerophospholipid O-acyltransferase 2 (MBOAT2) is a protein from Homo sapiens identified by UniProt accession Q6ZWT7, 520 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.
- UniProt accession: Q6ZWT7; gene symbol MBOAT2.
- Organism: Homo sapiens.
- Length: 520 amino acids.
- Top disease associations (Open Targets): calcium measurement, urate measurement and sleep duration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Membrane-bound glycerophospholipid O-acyltransferase 2 |
|---|---|
| UniProt accession | Q6ZWT7 |
| Gene | MBOAT2 |
| Organism | Homo sapiens |
| Length | 520 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (96)
Diseases linked to this target (Open Targets).
- calcium measurement · score 0.32
- urate measurement · score 0.29
- sleep duration · score 0.26
- uric acid measurement · score 0.26
- stomach disease · score 0.22
- atopic eczema · score 0.08
- pachyonychia congenita · score 0.08
- neoplasm · score 0.08
- drug use measurement · score 0.07
- lymphocyte count · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZWT7-F1 | alphafold | PREDICTED | 86.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZWT7.
Amino-acid sequence (520 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MBOAT2?
The strongest Open Targets associations for MBOAT2 are calcium measurement, urate measurement, sleep duration, uric acid measurement and stomach disease.
How long is the MBOAT2 protein?
The Homo sapiens MBOAT2 protein (UniProt Q6ZWT7) is 520 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZWT7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZWT7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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