Ubiquitin carboxyl-terminal hydrolase 51 (USP51)
Homo sapiens — UniProt Q70EK9
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin carboxyl-terminal hydrolase 51 (USP51) is a protein from Homo sapiens identified by UniProt accession Q70EK9, 711 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q70EK9; gene symbol USP51.
- Organism: Homo sapiens.
- Length: 711 amino acids.
- Top disease associations (Open Targets): Short stature, non-small cell lung carcinoma and osteoporosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin carboxyl-terminal hydrolase 51 |
|---|---|
| UniProt accession | Q70EK9 |
| Gene | USP51 |
| Organism | Homo sapiens |
| Length | 711 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- Short stature · score 0.33
- non-small cell lung carcinoma · score 0.09
- osteoporosis · score 0.05
- Osteoporosis · score 0.05
- melorheostosis · score 0.05
- dacryocystitis-osteopoikilosis syndrome · score 0.05
- 12q14 microdeletion syndrome · score 0.04
- pyknoachondrogenesis · score 0.04
- insulin resistance · score 0.04
- gnathodiaphyseal dysplasia · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q70EK9-F1 | alphafold | PREDICTED | 68.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q70EK9.
Amino-acid sequence (711 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with USP51?
The strongest Open Targets associations for USP51 are Short stature, non-small cell lung carcinoma, osteoporosis, Osteoporosis and melorheostosis.
How long is the USP51 protein?
The Homo sapiens USP51 protein (UniProt Q70EK9) is 711 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q70EK9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q70EK9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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