Mitochondrial S-adenosylmethionine carrier protein (SLC25A26)
Homo sapiens — UniProt Q70HW3
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) is a protein from Homo sapiens identified by UniProt accession Q70HW3, 274 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: Q70HW3; gene symbol SLC25A26.
- Organism: Homo sapiens.
- Length: 274 amino acids.
- Top disease associations (Open Targets): combined oxidative phosphorylation defect type 15, genetic disorder and mitochondrial disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial S-adenosylmethionine carrier protein |
|---|---|
| UniProt accession | Q70HW3 |
| Gene | SLC25A26 |
| Organism | Homo sapiens |
| Length | 274 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- combined oxidative phosphorylation defect type 15 · score 0.68
- genetic disorder · score 0.41
- mitochondrial disease · score 0.37
- mean corpuscular volume · score 0.31
- mean corpuscular hemoglobin concentration · score 0.29
- Red cell distribution width · score 0.29
- mean corpuscular hemoglobin · score 0.28
- hemoglobin measurement · score 0.24
- atrial fibrillation · score 0.22
- PR interval · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q70HW3-F1 | alphafold | PREDICTED | 87.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q70HW3.
Amino-acid sequence (274 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC25A26?
The strongest Open Targets associations for SLC25A26 are combined oxidative phosphorylation defect type 15, genetic disorder, mitochondrial disease, mean corpuscular volume and mean corpuscular hemoglobin concentration.
How long is the SLC25A26 protein?
The Homo sapiens SLC25A26 protein (UniProt Q70HW3) is 274 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q70HW3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q70HW3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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