Chondroitin sulfate synthase 3 (CHSY3)
Homo sapiens — UniProt Q70JA7
Data last refreshed: (UniProt release unknown)
Key facts
Chondroitin sulfate synthase 3 (CHSY3) is a protein from Homo sapiens identified by UniProt accession Q70JA7, 882 residues long. MolForge cross-references it against 0 known binders and 105 disease associations.
- UniProt accession: Q70JA7; gene symbol CHSY3.
- Organism: Homo sapiens.
- Length: 882 amino acids.
- Top disease associations (Open Targets): vital capacity, Red cell distribution width and forced expiratory volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Chondroitin sulfate synthase 3 |
|---|---|
| UniProt accession | Q70JA7 |
| Gene | CHSY3 |
| Organism | Homo sapiens |
| Length | 882 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (105)
Diseases linked to this target (Open Targets).
- vital capacity · score 0.43
- Red cell distribution width · score 0.32
- forced expiratory volume · score 0.31
- blood protein measurement · score 0.30
- mean platelet volume · score 0.16
- eosinophil count · score 0.16
- Crohn's disease · score 0.14
- body height · score 0.10
- Coxa Vara · score 0.08
- Coxa vara · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q70JA7-F1 | alphafold | PREDICTED | 76.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q70JA7.
Amino-acid sequence (882 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHSY3?
The strongest Open Targets associations for CHSY3 are vital capacity, Red cell distribution width, forced expiratory volume, blood protein measurement and mean platelet volume.
How long is the CHSY3 protein?
The Homo sapiens CHSY3 protein (UniProt Q70JA7) is 882 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q70JA7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q70JA7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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