Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP)
Homo sapiens — UniProt Q70UQ0
Data last refreshed: (UniProt release unknown)
Key facts
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) is a protein from Homo sapiens identified by UniProt accession Q70UQ0, 350 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q70UQ0; gene symbol IKBIP.
- Organism: Homo sapiens.
- Length: 350 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, pulse pressure measurement and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Inhibitor of nuclear factor kappa-B kinase-interacting protein |
|---|---|
| UniProt accession | Q70UQ0 |
| Gene | IKBIP |
| Organism | Homo sapiens |
| Length | 350 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.55
- pulse pressure measurement · score 0.30
- blood protein measurement · score 0.25
- metabolite measurement · score 0.24
- BMI-adjusted hip circumference · score 0.19
- neoplasm · score 0.09
- cancer · score 0.08
- smoking status measurement · score 0.08
- body fat percentage · score 0.08
- esophageal squamous cell carcinoma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q70UQ0-F1 | alphafold | PREDICTED | 82.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q70UQ0.
Amino-acid sequence (350 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IKBIP?
The strongest Open Targets associations for IKBIP are neurodegenerative disease, pulse pressure measurement, blood protein measurement, metabolite measurement and BMI-adjusted hip circumference.
How long is the IKBIP protein?
The Homo sapiens IKBIP protein (UniProt Q70UQ0) is 350 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q70UQ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q70UQ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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