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Staphylococcal nuclease domain-containing protein 1 (SND1)

Homo sapiens — UniProt Q7KZF4

Gene: SND1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Staphylococcal nuclease domain-containing protein 1 (SND1) is a protein from Homo sapiens identified by UniProt accession Q7KZF4, 910 residues long. MolForge cross-references it against 0 known binders and 242 disease associations.

  • UniProt accession: Q7KZF4; gene symbol SND1.
  • Organism: Homo sapiens.
  • Length: 910 amino acids.
  • Top disease associations (Open Targets): cancer, self reported educational attainment and prostate adenocarcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameStaphylococcal nuclease domain-containing protein 1
UniProt accessionQ7KZF4
GeneSND1
OrganismHomo sapiens
Length910 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (242)

Diseases linked to this target (Open Targets).

  • cancer · score 0.55
  • self reported educational attainment · score 0.37
  • prostate adenocarcinoma · score 0.37
  • lymphoid neoplasm · score 0.37
  • pancreatic ductal adenocarcinoma · score 0.37
  • pancreatic carcinoma · score 0.37
  • kidney neoplasm · score 0.37
  • esophageal adenocarcinoma · score 0.37
  • lung carcinoma · score 0.37
  • colorectal adenocarcinoma · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q7KZF4-F1alphafoldPREDICTED89.95—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7KZF4.

Amino-acid sequence (910 residues)

MASSAQSGGS SGGPAVPTVQ RGIIKMVLSG CAIIVRGQPR GGPPPERQIN LSNIRAGNLA RRAAATQPDA KDTPDEPWAF PAREFLRKKL IGKEVCFTIE NKTPQGREYG MIYLGKDTNG ENIAESLVAE GLATRREGMR ANNPEQNRLS ECEEQAKAAK KGMWSEGNGS HTIRDLKYTI ENPRHFVDSH HQKPVNAIIE HVRDGSVVRA LLLPDYYLVT VMLSGIKCPT FRREADGSET PEPFAAEAKF FTESRLLQRD VQIILESCHN QNILGTILHP NGNITELLLK EGFARCVDWS IAVYTRGAEK LRAAERFAKE RRLRIWRDYV APTANLDQKD KQFVAKVMQV LNADAIVVKL NSGDYKTIHL SSIRPPRLEG ENTQDKNKKL RPLYDIPYMF EAREFLRKKL IGKKVNVTVD YIRPASPATE TVPAFSERTC ATVTIGGINI AEALVSKGLA TVIRYRQDDD QRSSHYDELL AAEARAIKNG KGLHSKKEVP IHRVADISGD TQKAKQFLPF LQRAGRSEAV VEYVFSGSRL KLYLPKETCL ITFLLAGIEC PRGARNLPGL VQEGEPFSEE ATLFTKELVL QREVEVEVES MDKAGNFIGW LHIDGANLSV LLVEHALSKV HFTAERSSYY KSLLSAEEAA KQKKEKVWAH YEEQPVEEVM PVLEEKERSA SYKPVFVTEI TDDLHFYVQD VETGTQLEKL MENMRNDIAS HPPVEGSYAP RRGEFCIAKF VDGEWYRARV EKVESPAKIH VFYIDYGNRE VLPSTRLGTL SPAFSTRVLP AQATEYAFAF IQVPQDDDAR TDAVDSVVRD IQNTQCLLNV EHLSAGCPHV TLQFADSKGD VGLGLVKEGL VMVEVRKEKQ FQKVITEYLN AQESAKSARL NLWRYGDFRA DDADEFGYSR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SND1?

The strongest Open Targets associations for SND1 are cancer, self reported educational attainment, prostate adenocarcinoma, lymphoid neoplasm and pancreatic ductal adenocarcinoma.

How long is the SND1 protein?

The Homo sapiens SND1 protein (UniProt Q7KZF4) is 910 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ7KZF4
GeneSND1
OrganismHomo sapiens
Length910
Binders0
Diseases242
View on UniProt