TLR4 interactor with leucine rich repeats (TRIL)
Homo sapiens — UniProt Q7L0X0
Data last refreshed: (UniProt release unknown)
Key facts
TLR4 interactor with leucine rich repeats (TRIL) is a protein from Homo sapiens identified by UniProt accession Q7L0X0, 811 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.
- UniProt accession: Q7L0X0; gene symbol TRIL.
- Organism: Homo sapiens.
- Length: 811 amino acids.
- Top disease associations (Open Targets): serum gamma-glutamyl transferase measurement, age-related hearing impairment and lobe attachment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TLR4 interactor with leucine rich repeats |
|---|---|
| UniProt accession | Q7L0X0 |
| Gene | TRIL |
| Organism | Homo sapiens |
| Length | 811 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (65)
Diseases linked to this target (Open Targets).
- serum gamma-glutamyl transferase measurement · score 0.31
- age-related hearing impairment · score 0.27
- lobe attachment · score 0.24
- hair color · score 0.11
- body height · score 0.10
- lean body mass · score 0.10
- appendicular lean mass · score 0.10
- vital capacity · score 0.09
- fat body mass · score 0.09
- BMI-adjusted hip circumference · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L0X0-F1 | alphafold | PREDICTED | 71.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L0X0.
Amino-acid sequence (811 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRIL?
The strongest Open Targets associations for TRIL are serum gamma-glutamyl transferase measurement, age-related hearing impairment, lobe attachment, hair color and body height.
How long is the TRIL protein?
The Homo sapiens TRIL protein (UniProt Q7L0X0) is 811 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L0X0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L0X0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.