eIF5-mimic protein 2 (BZW1)
Homo sapiens — UniProt Q7L1Q6
Data last refreshed: (UniProt release unknown)
Key facts
eIF5-mimic protein 2 (BZW1) is a protein from Homo sapiens identified by UniProt accession Q7L1Q6, 419 residues long. MolForge cross-references it against 0 known binders and 86 disease associations.
- UniProt accession: Q7L1Q6; gene symbol BZW1.
- Organism: Homo sapiens.
- Length: 419 amino acids.
- Top disease associations (Open Targets): cancer, Red cell distribution width and serum gamma-glutamyl transferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | eIF5-mimic protein 2 |
|---|---|
| UniProt accession | Q7L1Q6 |
| Gene | BZW1 |
| Organism | Homo sapiens |
| Length | 419 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (86)
Diseases linked to this target (Open Targets).
- cancer · score 0.13
- Red cell distribution width · score 0.11
- serum gamma-glutamyl transferase measurement · score 0.08
- azoospermia · score 0.05
- Cataract-microcornea syndrome · score 0.04
- cochleosaccular degeneration-cataract syndrome · score 0.04
- Cochleosaccular degeneration - cataract · score 0.04
- pancreatic adenocarcinoma · score 0.04
- Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
- male infertility with teratozoospermia due to single gene mutation · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L1Q6-F1 | alphafold | PREDICTED | 91.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L1Q6.
Amino-acid sequence (419 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BZW1?
The strongest Open Targets associations for BZW1 are cancer, Red cell distribution width, serum gamma-glutamyl transferase measurement, azoospermia and Cataract-microcornea syndrome.
How long is the BZW1 protein?
The Homo sapiens BZW1 protein (UniProt Q7L1Q6) is 419 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L1Q6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L1Q6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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