Mitoguardin 2 (MIGA2)
Homo sapiens — UniProt Q7L4E1
Data last refreshed: (UniProt release unknown)
Key facts
Mitoguardin 2 (MIGA2) is a protein from Homo sapiens identified by UniProt accession Q7L4E1, 593 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q7L4E1; gene symbol MIGA2.
- Organism: Homo sapiens.
- Length: 593 amino acids.
- Top disease associations (Open Targets): protein measurement, neoplasm and atopic eczema.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitoguardin 2 |
|---|---|
| UniProt accession | Q7L4E1 |
| Gene | MIGA2 |
| Organism | Homo sapiens |
| Length | 593 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.04
- neoplasm · score 0.03
- atopic eczema · score 0.03
- polycystic ovary syndrome · score 0.03
- blood metabolite measurement · score 0.03
- mean platelet volume · score 0.02
- cognitive function measurement · score 0.02
- hemoglobin measurement · score 0.02
- erythrocyte count · score 0.02
- systolic blood pressure · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L4E1-F1 | alphafold | PREDICTED | 65.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L4E1.
Amino-acid sequence (593 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MIGA2?
The strongest Open Targets associations for MIGA2 are protein measurement, neoplasm, atopic eczema, polycystic ovary syndrome and blood metabolite measurement.
How long is the MIGA2 protein?
The Homo sapiens MIGA2 protein (UniProt Q7L4E1) is 593 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L4E1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L4E1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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