Golgi to ER traffic protein 4 homolog (GET4)
Homo sapiens — UniProt Q7L5D6
Data last refreshed: (UniProt release unknown)
Key facts
Golgi to ER traffic protein 4 homolog (GET4) is a protein from Homo sapiens identified by UniProt accession Q7L5D6, 327 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q7L5D6; gene symbol GET4.
- Organism: Homo sapiens.
- Length: 327 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Red cell distribution width and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Golgi to ER traffic protein 4 homolog |
|---|---|
| UniProt accession | Q7L5D6 |
| Gene | GET4 |
| Organism | Homo sapiens |
| Length | 327 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- Red cell distribution width · score 0.17
- body mass index · score 0.12
- forced expiratory volume · score 0.12
- IGF-1 measurement · score 0.11
- atrial fibrillation · score 0.11
- insulin like growth factor measurement · score 0.10
- PR interval · score 0.10
- hypertension · score 0.09
- vital capacity · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L5D6-F1 | alphafold | PREDICTED | 87.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L5D6.
Amino-acid sequence (327 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GET4?
The strongest Open Targets associations for GET4 are neurodegenerative disease, Red cell distribution width, body mass index, forced expiratory volume and IGF-1 measurement.
How long is the GET4 protein?
The Homo sapiens GET4 protein (UniProt Q7L5D6) is 327 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L5D6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L5D6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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