COP9 signalosome complex subunit 6 (COPS6)
Homo sapiens — UniProt Q7L5N1
Data last refreshed: (UniProt release unknown)
Key facts
COP9 signalosome complex subunit 6 (COPS6) is a protein from Homo sapiens identified by UniProt accession Q7L5N1, 327 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.
- UniProt accession: Q7L5N1; gene symbol COPS6.
- Organism: Homo sapiens.
- Length: 327 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, breast adenocarcinoma and erythrocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | COP9 signalosome complex subunit 6 |
|---|---|
| UniProt accession | Q7L5N1 |
| Gene | COPS6 |
| Organism | Homo sapiens |
| Length | 327 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (60)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- breast adenocarcinoma · score 0.18
- erythrocyte count · score 0.18
- hemoglobin measurement · score 0.16
- Familial prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- neoplasm · score 0.11
- cancer · score 0.10
- hepatocellular carcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L5N1-F1 | alphafold | PREDICTED | 84.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L5N1.
Amino-acid sequence (327 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COPS6?
The strongest Open Targets associations for COPS6 are neurodegenerative disease, breast adenocarcinoma, erythrocyte count, hemoglobin measurement and Familial prostate cancer.
How long is the COPS6 protein?
The Homo sapiens COPS6 protein (UniProt Q7L5N1) is 327 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L5N1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L5N1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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