Mitochondrial enolase superfamily member 1 (ENOSF1)
Homo sapiens — UniProt Q7L5Y1
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial enolase superfamily member 1 (ENOSF1) is a protein from Homo sapiens identified by UniProt accession Q7L5Y1, 443 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q7L5Y1; gene symbol ENOSF1.
- Organism: Homo sapiens.
- Length: 443 amino acids.
- Top disease associations (Open Targets): dyskeratosis congenita, digenic, dyskeratosis congenita and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial enolase superfamily member 1 |
|---|---|
| UniProt accession | Q7L5Y1 |
| Gene | ENOSF1 |
| Organism | Homo sapiens |
| Length | 443 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- dyskeratosis congenita, digenic · score 0.37
- dyskeratosis congenita · score 0.34
- protein measurement · score 0.34
- erythrocyte count · score 0.24
- benign neoplasm · score 0.22
- diastolic blood pressure · score 0.20
- systolic blood pressure · score 0.19
- serum metabolite measurement · score 0.19
- urinary metabolite measurement · score 0.19
- mean corpuscular volume · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L5Y1-F1 | alphafold | PREDICTED | 97.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L5Y1.
Amino-acid sequence (443 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ENOSF1?
The strongest Open Targets associations for ENOSF1 are dyskeratosis congenita, digenic, dyskeratosis congenita, protein measurement, erythrocyte count and benign neoplasm.
How long is the ENOSF1 protein?
The Homo sapiens ENOSF1 protein (UniProt Q7L5Y1) is 443 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L5Y1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L5Y1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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