Histone H2A type 3 (H2AC25)
Homo sapiens — UniProt Q7L7L0
Data last refreshed: (UniProt release unknown)
Key facts
Histone H2A type 3 (H2AC25) is a protein from Homo sapiens identified by UniProt accession Q7L7L0, 130 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q7L7L0; gene symbol H2AC25.
- Organism: Homo sapiens.
- Length: 130 amino acids.
- Top disease associations (Open Targets): viral disease, infectious disease and non-small cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Histone H2A type 3 |
|---|---|
| UniProt accession | Q7L7L0 |
| Gene | H2AC25 |
| Organism | Homo sapiens |
| Length | 130 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- viral disease · score 0.50
- infectious disease · score 0.50
- non-small cell lung carcinoma · score 0.05
- burn · score 0.05
- pancreatic neoplasm · score 0.05
- progressive supranuclear palsy · score 0.05
- metastatic melanoma · score 0.03
- neoplasm · score 0.02
- visceral Leishmaniasis · score 0.01
- Leishmaniasis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L7L0-F1 | alphafold | PREDICTED | 90.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L7L0.
Amino-acid sequence (130 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with H2AC25?
The strongest Open Targets associations for H2AC25 are viral disease, infectious disease, non-small cell lung carcinoma, burn and pancreatic neoplasm.
How long is the H2AC25 protein?
The Homo sapiens H2AC25 protein (UniProt Q7L7L0) is 130 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L7L0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L7L0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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