Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 (DHX32)
Homo sapiens — UniProt Q7L7V1
Data last refreshed: (UniProt release unknown)
Key facts
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 (DHX32) is a protein from Homo sapiens identified by UniProt accession Q7L7V1, 743 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q7L7V1; gene symbol DHX32.
- Organism: Homo sapiens.
- Length: 743 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, mean corpuscular hemoglobin concentration and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 |
|---|---|
| UniProt accession | Q7L7V1 |
| Gene | DHX32 |
| Organism | Homo sapiens |
| Length | 743 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.29
- mean corpuscular hemoglobin concentration · score 0.24
- mean corpuscular hemoglobin · score 0.24
- erythrocyte count · score 0.22
- Red cell distribution width · score 0.15
- red blood cell density measurement · score 0.13
- thyroid neoplasm · score 0.11
- appendicular lean mass · score 0.10
- blood protein measurement · score 0.09
- hepatocellular carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L7V1-F1 | alphafold | PREDICTED | 86.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L7V1.
Amino-acid sequence (743 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DHX32?
The strongest Open Targets associations for DHX32 are mean corpuscular volume, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, erythrocyte count and Red cell distribution width.
How long is the DHX32 protein?
The Homo sapiens DHX32 protein (UniProt Q7L7V1) is 743 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L7V1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L7V1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.