Serine/threonine-protein kinase TAO1 (TAOK1)
Homo sapiens — UniProt Q7L7X3
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase TAO1 (TAOK1) is a protein from Homo sapiens identified by UniProt accession Q7L7X3, 1001 residues long. MolForge cross-references it against 14 known binders and 167 disease associations.
- UniProt accession: Q7L7X3; gene symbol TAOK1.
- Organism: Homo sapiens.
- Length: 1001 amino acids.
- Top disease associations (Open Targets): developmental delay with or without intellectual impairment or behavioral abnormalities, neurodegenerative disease and Intellectual disability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase TAO1 |
|---|---|
| UniProt accession | Q7L7X3 |
| Gene | TAOK1 |
| Organism | Homo sapiens |
| Length | 1001 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (167)
Diseases linked to this target (Open Targets).
- developmental delay with or without intellectual impairment or behavioral abnormalities · score 0.67
- neurodegenerative disease · score 0.56
- Intellectual disability · score 0.56
- Neurodevelopmental disorder · score 0.52
- genetic disorder · score 0.51
- mean platelet volume · score 0.50
- platelet count · score 0.48
- lysosomal storage disease · score 0.46
- Global developmental delay · score 0.46
- neuroinflammatory disorder · score 0.45
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L7X3-F1 | alphafold | PREDICTED | 76.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L7X3.
Amino-acid sequence (1001 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAOK1?
The strongest Open Targets associations for TAOK1 are developmental delay with or without intellectual impairment or behavioral abnormalities, neurodegenerative disease, Intellectual disability, Neurodevelopmental disorder and genetic disorder.
How long is the TAOK1 protein?
The Homo sapiens TAOK1 protein (UniProt Q7L7X3) is 1001 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L7X3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L7X3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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