Tubulinyl-Tyr carboxypeptidase 1 (VASH1)
Homo sapiens — UniProt Q7L8A9
Data last refreshed: (UniProt release unknown)
Key facts
Tubulinyl-Tyr carboxypeptidase 1 (VASH1) is a protein from Homo sapiens identified by UniProt accession Q7L8A9, 365 residues long. MolForge cross-references it against 0 known binders and 130 disease associations.
- UniProt accession: Q7L8A9; gene symbol VASH1.
- Organism: Homo sapiens.
- Length: 365 amino acids.
- Top disease associations (Open Targets): bone density, urate measurement and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tubulinyl-Tyr carboxypeptidase 1 |
|---|---|
| UniProt accession | Q7L8A9 |
| Gene | VASH1 |
| Organism | Homo sapiens |
| Length | 365 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (130)
Diseases linked to this target (Open Targets).
- bone density · score 0.30
- urate measurement · score 0.30
- neoplasm · score 0.11
- cancer · score 0.09
- urinary bladder carcinoma · score 0.06
- acinar cell carcinoma · score 0.05
- Bartsocas-Papas syndrome 1 · score 0.05
- diabetic nephropathy · score 0.04
- breast carcinoma · score 0.04
- liver dysplastic nodule · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L8A9-F1 | alphafold | PREDICTED | 78.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L8A9.
Amino-acid sequence (365 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VASH1?
The strongest Open Targets associations for VASH1 are bone density, urate measurement, neoplasm, cancer and urinary bladder carcinoma.
How long is the VASH1 protein?
The Homo sapiens VASH1 protein (UniProt Q7L8A9) is 365 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L8A9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L8A9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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