SH3 domain-binding protein 5-like (SH3BP5L)
Homo sapiens — UniProt Q7L8J4
Data last refreshed: (UniProt release unknown)
Key facts
SH3 domain-binding protein 5-like (SH3BP5L) is a protein from Homo sapiens identified by UniProt accession Q7L8J4, 393 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.
- UniProt accession: Q7L8J4; gene symbol SH3BP5L.
- Organism: Homo sapiens.
- Length: 393 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, cyst and metastatic melanoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SH3 domain-binding protein 5-like |
|---|---|
| UniProt accession | Q7L8J4 |
| Gene | SH3BP5L |
| Organism | Homo sapiens |
| Length | 393 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (3)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.06
- cyst · score 0.02
- metastatic melanoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L8J4-F1 | alphafold | PREDICTED | 72.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L8J4.
Amino-acid sequence (393 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SH3BP5L?
The strongest Open Targets associations for SH3BP5L are mean corpuscular volume, cyst and metastatic melanoma.
How long is the SH3BP5L protein?
The Homo sapiens SH3BP5L protein (UniProt Q7L8J4) is 393 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L8J4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L8J4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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