FAST kinase domain-containing protein 5, mitochondrial (FASTKD5)
Homo sapiens — UniProt Q7L8L6
Data last refreshed: (UniProt release unknown)
Key facts
FAST kinase domain-containing protein 5, mitochondrial (FASTKD5) is a protein from Homo sapiens identified by UniProt accession Q7L8L6, 764 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q7L8L6; gene symbol FASTKD5.
- Organism: Homo sapiens.
- Length: 764 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, leukocyte count and wellbeing measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | FAST kinase domain-containing protein 5, mitochondrial |
|---|---|
| UniProt accession | Q7L8L6 |
| Gene | FASTKD5 |
| Organism | Homo sapiens |
| Length | 764 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- leukocyte count · score 0.11
- wellbeing measurement · score 0.08
- self reported educational attainment · score 0.07
- Romano-Ward syndrome · score 0.05
- Arrhythmogenic right ventricular dysplasia · score 0.05
- Familial short QT syndrome · score 0.05
- Brugada syndrome · score 0.05
- familial atrial fibrillation · score 0.05
- Wolff-Parkinson-White Syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L8L6-F1 | alphafold | PREDICTED | 78.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L8L6.
Amino-acid sequence (764 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FASTKD5?
The strongest Open Targets associations for FASTKD5 are neurodegenerative disease, leukocyte count, wellbeing measurement, self reported educational attainment and Romano-Ward syndrome.
How long is the FASTKD5 protein?
The Homo sapiens FASTKD5 protein (UniProt Q7L8L6) is 764 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L8L6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L8L6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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