OTU domain-containing protein 6A (OTUD6A)
Homo sapiens — UniProt Q7L8S5
Data last refreshed: (UniProt release unknown)
Key facts
OTU domain-containing protein 6A (OTUD6A) is a protein from Homo sapiens identified by UniProt accession Q7L8S5, 288 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q7L8S5; gene symbol OTUD6A.
- Organism: Homo sapiens.
- Length: 288 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cancer and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | OTU domain-containing protein 6A |
|---|---|
| UniProt accession | Q7L8S5 |
| Gene | OTUD6A |
| Organism | Homo sapiens |
| Length | 288 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.20
- cancer · score 0.08
- neoplasm · score 0.06
- cholesterol-ester transfer protein deficiency · score 0.04
- hypertriglyceridemia 2 · score 0.04
- Combined hyperlipidemia · score 0.04
- chronic myeloproliferative disorder · score 0.03
- linear and whorled nevoid hypermelanosis · score 0.03
- homozygous familial hypercholesterolemia · score 0.03
- thyroid hormone metabolism, abnormal, 2 · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L8S5-F1 | alphafold | PREDICTED | 82.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L8S5.
Amino-acid sequence (288 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OTUD6A?
The strongest Open Targets associations for OTUD6A are neurodegenerative disease, cancer, neoplasm, cholesterol-ester transfer protein deficiency and hypertriglyceridemia 2.
How long is the OTUD6A protein?
The Homo sapiens OTUD6A protein (UniProt Q7L8S5) is 288 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L8S5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L8S5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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