Endonuclease/exonuclease/phosphatase family domain-containing protein 1 (EEPD1)
Homo sapiens — UniProt Q7L9B9
Data last refreshed: (UniProt release unknown)
Key facts
Endonuclease/exonuclease/phosphatase family domain-containing protein 1 (EEPD1) is a protein from Homo sapiens identified by UniProt accession Q7L9B9, 569 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.
- UniProt accession: Q7L9B9; gene symbol EEPD1.
- Organism: Homo sapiens.
- Length: 569 amino acids.
- Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, reticulocyte count and low density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Endonuclease/exonuclease/phosphatase family domain-containing protein 1 |
|---|---|
| UniProt accession | Q7L9B9 |
| Gene | EEPD1 |
| Organism | Homo sapiens |
| Length | 569 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (65)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.44
- reticulocyte count · score 0.43
- low density lipoprotein cholesterol measurement · score 0.42
- reticulocyte measurement · score 0.42
- C-reactive protein measurement · score 0.41
- platelet count · score 0.40
- leukocyte count · score 0.39
- neutrophil count · score 0.39
- lymphocyte count · score 0.38
- protein measurement · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L9B9-F1 | alphafold | PREDICTED | 74.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L9B9.
Amino-acid sequence (569 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EEPD1?
The strongest Open Targets associations for EEPD1 are high density lipoprotein cholesterol measurement, reticulocyte count, low density lipoprotein cholesterol measurement, reticulocyte measurement and C-reactive protein measurement.
How long is the EEPD1 protein?
The Homo sapiens EEPD1 protein (UniProt Q7L9B9) is 569 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L9B9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L9B9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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