MOB kinase activator 1B (MOB1B)
Homo sapiens — UniProt Q7L9L4
Data last refreshed: (UniProt release unknown)
Key facts
MOB kinase activator 1B (MOB1B) is a protein from Homo sapiens identified by UniProt accession Q7L9L4, 216 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q7L9L4; gene symbol MOB1B.
- Organism: Homo sapiens.
- Length: 216 amino acids.
- Top disease associations (Open Targets): type 2 diabetes mellitus, mean corpuscular volume and Drugs used in diabetes use measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MOB kinase activator 1B |
|---|---|
| UniProt accession | Q7L9L4 |
| Gene | MOB1B |
| Organism | Homo sapiens |
| Length | 216 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.32
- mean corpuscular volume · score 0.22
- Drugs used in diabetes use measurement · score 0.17
- bone density · score 0.14
- urate measurement · score 0.14
- C-X-C motif chemokine 10 measurement · score 0.10
- mean reticulocyte volume · score 0.08
- triglyceride measurement · score 0.08
- Red cell distribution width · score 0.07
- mean corpuscular hemoglobin concentration · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7L9L4-F1 | alphafold | PREDICTED | 88.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7L9L4.
Amino-acid sequence (216 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MOB1B?
The strongest Open Targets associations for MOB1B are type 2 diabetes mellitus, mean corpuscular volume, Drugs used in diabetes use measurement, bone density and urate measurement.
How long is the MOB1B protein?
The Homo sapiens MOB1B protein (UniProt Q7L9L4) is 216 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7L9L4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7L9L4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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