Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1)
Homo sapiens — UniProt Q7Z2W4
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) is a protein from Homo sapiens identified by UniProt accession Q7Z2W4, 902 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: Q7Z2W4; gene symbol ZC3HAV1.
- Organism: Homo sapiens.
- Length: 902 amino acids.
- Top disease associations (Open Targets): cancer, eosinophil count and eosinophil percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger CCCH-type antiviral protein 1 |
|---|---|
| UniProt accession | Q7Z2W4 |
| Gene | ZC3HAV1 |
| Organism | Homo sapiens |
| Length | 902 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- cancer · score 0.54
- eosinophil count · score 0.46
- eosinophil percentage of leukocytes · score 0.41
- neurodegenerative disease · score 0.36
- lymphocyte count · score 0.35
- platelet count · score 0.29
- leukocyte count · score 0.26
- myeloid white cell count · score 0.24
- platelet crit · score 0.24
- serum albumin measurement · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z2W4-F1 | alphafold | PREDICTED | 69.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z2W4.
Amino-acid sequence (902 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZC3HAV1?
The strongest Open Targets associations for ZC3HAV1 are cancer, eosinophil count, eosinophil percentage of leukocytes, neurodegenerative disease and lymphocyte count.
How long is the ZC3HAV1 protein?
The Homo sapiens ZC3HAV1 protein (UniProt Q7Z2W4) is 902 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z2W4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z2W4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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