Trafficking protein particle complex subunit 11 (TRAPPC11)
Homo sapiens — UniProt Q7Z392
Data last refreshed: (UniProt release unknown)
Key facts
Trafficking protein particle complex subunit 11 (TRAPPC11) is a protein from Homo sapiens identified by UniProt accession Q7Z392, 1133 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q7Z392; gene symbol TRAPPC11.
- Organism: Homo sapiens.
- Length: 1133 amino acids.
- Top disease associations (Open Targets): autosomal recessive limb-girdle muscular dystrophy type R18, limb-girdle muscular dystrophy and Autosomal recessive limb-girdle muscular dystrophy type 2S.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Trafficking protein particle complex subunit 11 |
|---|---|
| UniProt accession | Q7Z392 |
| Gene | TRAPPC11 |
| Organism | Homo sapiens |
| Length | 1133 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- autosomal recessive limb-girdle muscular dystrophy type R18 · score 0.79
- limb-girdle muscular dystrophy · score 0.57
- Autosomal recessive limb-girdle muscular dystrophy type 2S · score 0.52
- autosomal recessive limb-girdle muscular dystrophy · score 0.50
- neurodegenerative disease · score 0.48
- genetic disorder · score 0.47
- muscular dystrophy, limb-girdle, autosomal recessive 23 · score 0.41
- Triple A syndrome · score 0.37
- intellectual disability-hyperkinetic movement-truncal ataxia syndrome · score 0.37
- Alzheimer disease · score 0.36
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z392-F1 | alphafold | PREDICTED | 87.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z392.
Amino-acid sequence (1133 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRAPPC11?
The strongest Open Targets associations for TRAPPC11 are autosomal recessive limb-girdle muscular dystrophy type R18, limb-girdle muscular dystrophy, Autosomal recessive limb-girdle muscular dystrophy type 2S, autosomal recessive limb-girdle muscular dystrophy and neurodegenerative disease.
How long is the TRAPPC11 protein?
The Homo sapiens TRAPPC11 protein (UniProt Q7Z392) is 1133 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z392 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z392 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.