Autophagy-related protein 9A (ATG9A)
Homo sapiens — UniProt Q7Z3C6
Data last refreshed: (UniProt release unknown)
Key facts
Autophagy-related protein 9A (ATG9A) is a protein from Homo sapiens identified by UniProt accession Q7Z3C6, 839 residues long. MolForge cross-references it against 0 known binders and 104 disease associations.
- UniProt accession: Q7Z3C6; gene symbol ATG9A.
- Organism: Homo sapiens.
- Length: 839 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lysosomal storage disease and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Autophagy-related protein 9A |
|---|---|
| UniProt accession | Q7Z3C6 |
| Gene | ATG9A |
| Organism | Homo sapiens |
| Length | 839 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (104)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- lysosomal storage disease · score 0.37
- breast adenocarcinoma · score 0.18
- triglyceride measurement · score 0.14
- mean platelet volume · score 0.14
- lymphocyte count · score 0.14
- platelet component distribution width · score 0.12
- high density lipoprotein cholesterol measurement · score 0.12
- reticulocyte count · score 0.10
- Red cell distribution width · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z3C6-F1 | alphafold | PREDICTED | 73.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z3C6.
Amino-acid sequence (839 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATG9A?
The strongest Open Targets associations for ATG9A are neurodegenerative disease, lysosomal storage disease, breast adenocarcinoma, triglyceride measurement and mean platelet volume.
How long is the ATG9A protein?
The Homo sapiens ATG9A protein (UniProt Q7Z3C6) is 839 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z3C6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z3C6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.