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LisH domain-containing protein ARMC9 (ARMC9)

Homo sapiens — UniProt Q7Z3E5

Gene: ARMC9Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

LisH domain-containing protein ARMC9 (ARMC9) is a protein from Homo sapiens identified by UniProt accession Q7Z3E5, 818 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

  • UniProt accession: Q7Z3E5; gene symbol ARMC9.
  • Organism: Homo sapiens.
  • Length: 818 amino acids.
  • Top disease associations (Open Targets): Joubert syndrome, creatinine measurement and Intellectual disability.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameLisH domain-containing protein ARMC9
UniProt accessionQ7Z3E5
GeneARMC9
OrganismHomo sapiens
Length818 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (44)

Diseases linked to this target (Open Targets).

  • Joubert syndrome · score 0.79
  • creatinine measurement · score 0.37
  • Intellectual disability · score 0.37
  • Dandy-Walker syndrome · score 0.32
  • PHF-tau measurement · score 0.30
  • cystatin C measurement · score 0.29
  • Vertigo · score 0.29
  • aspartate aminotransferase measurement · score 0.28
  • glomerular filtration rate · score 0.28
  • mean corpuscular volume · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q7Z3E5-F1alphafoldPREDICTED70.86—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z3E5.

Amino-acid sequence (818 residues)

MGDILAHESE LLGLVKEYLD FAEFEDTLKT FSKECKIKGK PLCKTVGGSF RDSKSLTIQK DLVAAFDNGD QKVFFDLWEE HISSSIRDGD SFAQKLEFYL HIHFAIYLLK YSVGRPDKEE LDEKISYFKT YLETKGAALS QTTEFLPFYA LPFVPNPMVH PSFKELFQDS WTPELKLKLI KFLALISKAS NTPKLLTIYK ENGQSNKEIL QQLHQQLVEA ERRSVTYLKR YNKIQADYHN LIGVTAELVD SLEATVSGKM ITPEYLQSVC VRLFSNQMRQ SLAHSVDFTR PGTASTMLRA SLAPVKLKDV PLLPSLDYEK LKKDLILGSD RLKAFLLQAL RWRLTTSHPG EQRETVLQAY ISNDLLDCYS HNQRSVLQLL HSTSDVVRQY MARLINAFAS LAEGRLYLAQ NTKVLQMLEG RLKEEDKDII TRENVLGALQ KFSLRRPLQT AMIQDGLIFW LVDVLKDPDC LSDYTLEYSV ALLMNLCLRS TGKNMCAKVA GLVLKVLSDL LGHENHEIQP YVNGALYSIL SVPSIREEAR AMGMEDILRC FIKEGNAEMI RQIEFIIKQL NSEELPDGVL ESDDDEDEDD EEDHDIMEAD LDKDELIQPQ LGELSGEKLL TTEYLGIMTN TGKTRRKGLA NVQWSGDEPL QRPVTPGGHR NGYPVVEDQH TPPQTAQHAR NGHPQALPAA HEAVYREGKP STPESCVSSS SAIIAKPGEW LPRGRQEEPR PAPTGTPRQP REAPQDPGNG VTTRECASAF TCKPRAPCTP EMLDWNPPKA KASVLAPLFS SCGPQQASRP GSTASSTRGL PSSQSHRK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ARMC9?

The strongest Open Targets associations for ARMC9 are Joubert syndrome, creatinine measurement, Intellectual disability, Dandy-Walker syndrome and PHF-tau measurement.

How long is the ARMC9 protein?

The Homo sapiens ARMC9 protein (UniProt Q7Z3E5) is 818 amino acids long.

Browse: Targets: A · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ7Z3E5
GeneARMC9
OrganismHomo sapiens
Length818
Binders0
Diseases44
View on UniProt