Photoreceptor ankyrin repeat protein (ANKRD33)
Homo sapiens — UniProt Q7Z3H0
Data last refreshed: (UniProt release unknown)
Key facts
Photoreceptor ankyrin repeat protein (ANKRD33) is a protein from Homo sapiens identified by UniProt accession Q7Z3H0, 452 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q7Z3H0; gene symbol ANKRD33.
- Organism: Homo sapiens.
- Length: 452 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, erythrocyte count and hemoglobin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Photoreceptor ankyrin repeat protein |
|---|---|
| UniProt accession | Q7Z3H0 |
| Gene | ANKRD33 |
| Organism | Homo sapiens |
| Length | 452 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.23
- erythrocyte count · score 0.17
- hemoglobin measurement · score 0.15
- hematocrit · score 0.15
- urate measurement · score 0.08
- uric acid measurement · score 0.06
- HMG CoA reductase inhibitor use measurement · score 0.05
- colorectal adenocarcinoma · score 0.04
- breast carcinoma · score 0.04
- metabolite measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z3H0-F1 | alphafold | PREDICTED | 60.49 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z3H0.
Amino-acid sequence (452 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD33?
The strongest Open Targets associations for ANKRD33 are neurodegenerative disease, erythrocyte count, hemoglobin measurement, hematocrit and urate measurement.
How long is the ANKRD33 protein?
The Homo sapiens ANKRD33 protein (UniProt Q7Z3H0) is 452 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z3H0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z3H0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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