Mesoderm induction early response protein 3 (MIER3)
Homo sapiens — UniProt Q7Z3K6
Data last refreshed: (UniProt release unknown)
Key facts
Mesoderm induction early response protein 3 (MIER3) is a protein from Homo sapiens identified by UniProt accession Q7Z3K6, 550 residues long. MolForge cross-references it against 0 known binders and 122 disease associations.
- UniProt accession: Q7Z3K6; gene symbol MIER3.
- Organism: Homo sapiens.
- Length: 550 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, sex hormone-binding globulin measurement and breast carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mesoderm induction early response protein 3 |
|---|---|
| UniProt accession | Q7Z3K6 |
| Gene | MIER3 |
| Organism | Homo sapiens |
| Length | 550 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (122)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- sex hormone-binding globulin measurement · score 0.36
- breast carcinoma · score 0.30
- adolescent idiopathic scoliosis · score 0.22
- diastolic blood pressure · score 0.21
- body height · score 0.15
- diffuse plaque measurement · score 0.14
- triglyceride measurement · score 0.09
- type 2 diabetes mellitus · score 0.09
- BMI-adjusted waist-hip ratio · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z3K6-F1 | alphafold | PREDICTED | 57.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z3K6.
Amino-acid sequence (550 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MIER3?
The strongest Open Targets associations for MIER3 are neurodegenerative disease, sex hormone-binding globulin measurement, breast carcinoma, adolescent idiopathic scoliosis and diastolic blood pressure.
How long is the MIER3 protein?
The Homo sapiens MIER3 protein (UniProt Q7Z3K6) is 550 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z3K6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z3K6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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