Notch homolog 2 N-terminal-like protein A (NOTCH2NLA)
Homo sapiens — UniProt Q7Z3S9
Data last refreshed: (UniProt release unknown)
Key facts
Notch homolog 2 N-terminal-like protein A (NOTCH2NLA) is a protein from Homo sapiens identified by UniProt accession Q7Z3S9, 236 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.
- UniProt accession: Q7Z3S9; gene symbol NOTCH2NLA.
- Organism: Homo sapiens.
- Length: 236 amino acids.
- Top disease associations (Open Targets): psoriatic arthritis and plasmacytoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Notch homolog 2 N-terminal-like protein A |
|---|---|
| UniProt accession | Q7Z3S9 |
| Gene | NOTCH2NLA |
| Organism | Homo sapiens |
| Length | 236 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (2)
Diseases linked to this target (Open Targets).
- psoriatic arthritis · score 0.00
- plasmacytoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z3S9-F1 | alphafold | PREDICTED | 87.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z3S9.
Amino-acid sequence (236 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NOTCH2NLA?
The strongest Open Targets associations for NOTCH2NLA are psoriatic arthritis and plasmacytoma.
How long is the NOTCH2NLA protein?
The Homo sapiens NOTCH2NLA protein (UniProt Q7Z3S9) is 236 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z3S9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z3S9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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