Low-density lipoprotein receptor-related protein 10 (LRP10)
Homo sapiens — UniProt Q7Z4F1
Data last refreshed: (UniProt release unknown)
Key facts
Low-density lipoprotein receptor-related protein 10 (LRP10) is a protein from Homo sapiens identified by UniProt accession Q7Z4F1, 713 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q7Z4F1; gene symbol LRP10.
- Organism: Homo sapiens.
- Length: 713 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, ovarian cancer and lung adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Low-density lipoprotein receptor-related protein 10 |
|---|---|
| UniProt accession | Q7Z4F1 |
| Gene | LRP10 |
| Organism | Homo sapiens |
| Length | 713 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- ovarian cancer · score 0.25
- lung adenocarcinoma · score 0.22
- body height · score 0.21
- cutaneous melanoma · score 0.18
- head and neck squamous cell carcinoma · score 0.15
- esophageal cancer · score 0.12
- glioblastoma multiforme · score 0.12
- myoepithelial tumor · score 0.11
- bladder exstrophy · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z4F1-F1 | alphafold | PREDICTED | 67.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z4F1.
Amino-acid sequence (713 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRP10?
The strongest Open Targets associations for LRP10 are neurodegenerative disease, ovarian cancer, lung adenocarcinoma, body height and cutaneous melanoma.
How long is the LRP10 protein?
The Homo sapiens LRP10 protein (UniProt Q7Z4F1) is 713 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z4F1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z4F1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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