COMM domain-containing protein 6 (COMMD6)
Homo sapiens — UniProt Q7Z4G1
Data last refreshed: (UniProt release unknown)
Key facts
COMM domain-containing protein 6 (COMMD6) is a protein from Homo sapiens identified by UniProt accession Q7Z4G1, 85 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q7Z4G1; gene symbol COMMD6.
- Organism: Homo sapiens.
- Length: 85 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean corpuscular volume and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | COMM domain-containing protein 6 |
|---|---|
| UniProt accession | Q7Z4G1 |
| Gene | COMMD6 |
| Organism | Homo sapiens |
| Length | 85 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- mean corpuscular volume · score 0.09
- appendicular lean mass · score 0.08
- mean corpuscular hemoglobin · score 0.08
- neoplasm · score 0.08
- diet measurement · score 0.06
- respiratory tract infectious disorder · score 0.06
- sinusitis · score 0.04
- erythrocyte count · score 0.03
- eosinophil count · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z4G1-F1 | alphafold | PREDICTED | 84.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z4G1.
Amino-acid sequence (85 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COMMD6?
The strongest Open Targets associations for COMMD6 are neurodegenerative disease, mean corpuscular volume, appendicular lean mass, mean corpuscular hemoglobin and neoplasm.
How long is the COMMD6 protein?
The Homo sapiens COMMD6 protein (UniProt Q7Z4G1) is 85 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z4G1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z4G1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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