5'-deoxynucleotidase HDDC2 (HDDC2)
Homo sapiens — UniProt Q7Z4H3
Data last refreshed: (UniProt release unknown)
Key facts
5'-deoxynucleotidase HDDC2 (HDDC2) is a protein from Homo sapiens identified by UniProt accession Q7Z4H3, 204 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q7Z4H3; gene symbol HDDC2.
- Organism: Homo sapiens.
- Length: 204 amino acids.
- Top disease associations (Open Targets): hemoglobin measurement, hematocrit and erythrocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | 5'-deoxynucleotidase HDDC2 |
|---|---|
| UniProt accession | Q7Z4H3 |
| Gene | HDDC2 |
| Organism | Homo sapiens |
| Length | 204 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.42
- hematocrit · score 0.40
- erythrocyte count · score 0.40
- red blood cell density measurement · score 0.35
- electrocardiography · score 0.27
- mean corpuscular hemoglobin concentration · score 0.27
- gut microbiome measurement · score 0.25
- central nervous system disease · score 0.25
- balding measurement · score 0.16
- hemoglobin E-beta-thalassemia syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z4H3-F1 | alphafold | PREDICTED | 94.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z4H3.
Amino-acid sequence (204 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HDDC2?
The strongest Open Targets associations for HDDC2 are hemoglobin measurement, hematocrit, erythrocyte count, red blood cell density measurement and electrocardiography.
How long is the HDDC2 protein?
The Homo sapiens HDDC2 protein (UniProt Q7Z4H3) is 204 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z4H3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z4H3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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