Protein O-glucosyltransferase 3 (POGLUT3)
Homo sapiens — UniProt Q7Z4H8
Data last refreshed: (UniProt release unknown)
Key facts
Protein O-glucosyltransferase 3 (POGLUT3) is a protein from Homo sapiens identified by UniProt accession Q7Z4H8, 507 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q7Z4H8; gene symbol POGLUT3.
- Organism: Homo sapiens.
- Length: 507 amino acids.
- Top disease associations (Open Targets): blood protein measurement, platelet crit and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein O-glucosyltransferase 3 |
|---|---|
| UniProt accession | Q7Z4H8 |
| Gene | POGLUT3 |
| Organism | Homo sapiens |
| Length | 507 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.41
- platelet crit · score 0.40
- mean corpuscular volume · score 0.36
- Immature Reticulocyte Fraction Measurement · score 0.33
- reticulocyte measurement · score 0.32
- mean reticulocyte volume · score 0.24
- prostate carcinoma · score 0.24
- erythrocyte count · score 0.24
- cancer · score 0.22
- leukocyte count · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z4H8-F1 | alphafold | PREDICTED | 92.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z4H8.
Amino-acid sequence (507 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with POGLUT3?
The strongest Open Targets associations for POGLUT3 are blood protein measurement, platelet crit, mean corpuscular volume, Immature Reticulocyte Fraction Measurement and reticulocyte measurement.
How long is the POGLUT3 protein?
The Homo sapiens POGLUT3 protein (UniProt Q7Z4H8) is 507 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z4H8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z4H8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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