Protein FAM220A (FAM220A)
Homo sapiens — UniProt Q7Z4H9
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM220A (FAM220A) is a protein from Homo sapiens identified by UniProt accession Q7Z4H9, 259 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q7Z4H9; gene symbol FAM220A.
- Organism: Homo sapiens.
- Length: 259 amino acids.
- Top disease associations (Open Targets): C-reactive protein measurement, lymphocyte percentage of leukocytes and lean body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM220A |
|---|---|
| UniProt accession | Q7Z4H9 |
| Gene | FAM220A |
| Organism | Homo sapiens |
| Length | 259 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- C-reactive protein measurement · score 0.33
- lymphocyte percentage of leukocytes · score 0.31
- lean body mass · score 0.30
- fat body mass · score 0.28
- neutrophil percentage of leukocytes · score 0.28
- hip circumference · score 0.26
- neurodegenerative disease · score 0.25
- body weight · score 0.20
- base metabolic rate measurement · score 0.12
- whole body water mass · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z4H9-F1 | alphafold | PREDICTED | 47.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z4H9.
Amino-acid sequence (259 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM220A?
The strongest Open Targets associations for FAM220A are C-reactive protein measurement, lymphocyte percentage of leukocytes, lean body mass, fat body mass and neutrophil percentage of leukocytes.
How long is the FAM220A protein?
The Homo sapiens FAM220A protein (UniProt Q7Z4H9) is 259 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z4H9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z4H9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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