Putative glycosyltransferase 6 domain-containing protein 1 (GLT6D1)
Homo sapiens — UniProt Q7Z4J2
Data last refreshed: (UniProt release unknown)
Key facts
Putative glycosyltransferase 6 domain-containing protein 1 (GLT6D1) is a protein from Homo sapiens identified by UniProt accession Q7Z4J2, 276 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q7Z4J2; gene symbol GLT6D1.
- Organism: Homo sapiens.
- Length: 276 amino acids.
- Top disease associations (Open Targets): neuroinflammatory disorder, periodontitis and multiple sclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative glycosyltransferase 6 domain-containing protein 1 |
|---|---|
| UniProt accession | Q7Z4J2 |
| Gene | GLT6D1 |
| Organism | Homo sapiens |
| Length | 276 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- neuroinflammatory disorder · score 0.26
- periodontitis · score 0.26
- multiple sclerosis · score 0.24
- neurodegenerative disease · score 0.24
- lysosomal storage disease · score 0.24
- Alzheimer disease · score 0.24
- Parkinson disease · score 0.24
- urate measurement · score 0.03
- bone density · score 0.03
- alkaline phosphatase measurement · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z4J2-F1 | alphafold | PREDICTED | 91.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z4J2.
Amino-acid sequence (276 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GLT6D1?
The strongest Open Targets associations for GLT6D1 are neuroinflammatory disorder, periodontitis, multiple sclerosis, neurodegenerative disease and lysosomal storage disease.
How long is the GLT6D1 protein?
The Homo sapiens GLT6D1 protein (UniProt Q7Z4J2) is 276 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z4J2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z4J2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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