Cytochrome c oxidase subunit 8C, mitochondrial (COX8C)
Homo sapiens — UniProt Q7Z4L0
Data last refreshed: (UniProt release unknown)
Key facts
Cytochrome c oxidase subunit 8C, mitochondrial (COX8C) is a protein from Homo sapiens identified by UniProt accession Q7Z4L0, 72 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q7Z4L0; gene symbol COX8C.
- Organism: Homo sapiens.
- Length: 72 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mathematical ability and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytochrome c oxidase subunit 8C, mitochondrial |
|---|---|
| UniProt accession | Q7Z4L0 |
| Gene | COX8C |
| Organism | Homo sapiens |
| Length | 72 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.24
- mathematical ability · score 0.09
- body mass index · score 0.09
- age at first sexual intercourse measurement · score 0.06
- body fat percentage · score 0.06
- wheezing · score 0.06
- sodium measurement · score 0.06
- IGF-1 measurement · score 0.06
- age at menarche · score 0.05
- puberty onset measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z4L0-F1 | alphafold | PREDICTED | 79.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z4L0.
Amino-acid sequence (72 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COX8C?
The strongest Open Targets associations for COX8C are neurodegenerative disease, mathematical ability, body mass index, age at first sexual intercourse measurement and body fat percentage.
How long is the COX8C protein?
The Homo sapiens COX8C protein (UniProt Q7Z4L0) is 72 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z4L0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z4L0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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