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UPF0669 protein C6orf120 (C6orf120)

Homo sapiens — UniProt Q7Z4R8

Gene: C6orf120Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

UPF0669 protein C6orf120 (C6orf120) is a protein from Homo sapiens identified by UniProt accession Q7Z4R8, 191 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

  • UniProt accession: Q7Z4R8; gene symbol C6orf120.
  • Organism: Homo sapiens.
  • Length: 191 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, self reported educational attainment and eye morphology measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUPF0669 protein C6orf120
UniProt accessionQ7Z4R8
GeneC6orf120
OrganismHomo sapiens
Length191 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (24)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.30
  • self reported educational attainment · score 0.21
  • eye morphology measurement · score 0.15
  • smoking status measurement · score 0.13
  • attention deficit hyperactivity disorder · score 0.09
  • substance abuse · score 0.09
  • antisocial behaviour measurement · score 0.09
  • insomnia measurement · score 0.07
  • insomnia · score 0.07
  • neutrophil count · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q7Z4R8-F1alphafoldPREDICTED79.79—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z4R8.

Amino-acid sequence (191 residues)

MAAPRGRAAP WTTALLLLLA SQVLSPGSCA DEEEVPEEWV LLHVVQGQIG AGNYSYLRLN HEGKIVLRMR SLKGDADLYV SASSLHPSFD DYELQSATCG PDAVSIPAHF RRPVGIGVYG HPSHLESEFE MKVYYDGTVE QHPFGEAAYP ADGADAGQKH AGAPEDASQE EESVLWTILI SILKLVLEIL F

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C6orf120?

The strongest Open Targets associations for C6orf120 are neurodegenerative disease, self reported educational attainment, eye morphology measurement, smoking status measurement and attention deficit hyperactivity disorder.

How long is the C6orf120 protein?

The Homo sapiens C6orf120 protein (UniProt Q7Z4R8) is 191 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ7Z4R8
GeneC6orf120
OrganismHomo sapiens
Length191
Binders0
Diseases24
View on UniProt