Zinc finger protein 438 (ZNF438)
Homo sapiens — UniProt Q7Z4V0
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 438 (ZNF438) is a protein from Homo sapiens identified by UniProt accession Q7Z4V0, 828 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: Q7Z4V0; gene symbol ZNF438.
- Organism: Homo sapiens.
- Length: 828 amino acids.
- Top disease associations (Open Targets): vital capacity, body height and cortical thickness.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 438 |
|---|---|
| UniProt accession | Q7Z4V0 |
| Gene | ZNF438 |
| Organism | Homo sapiens |
| Length | 828 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- vital capacity · score 0.45
- body height · score 0.45
- cortical thickness · score 0.44
- neuroimaging measurement · score 0.42
- brain measurement · score 0.42
- FEV/FVC ratio · score 0.40
- cortical surface area measurement · score 0.38
- rheumatoid arthritis · score 0.37
- multiple sclerosis · score 0.37
- mathematical ability · score 0.36
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z4V0-F1 | alphafold | PREDICTED | 49.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z4V0.
Amino-acid sequence (828 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF438?
The strongest Open Targets associations for ZNF438 are vital capacity, body height, cortical thickness, neuroimaging measurement and brain measurement.
How long is the ZNF438 protein?
The Homo sapiens ZNF438 protein (UniProt Q7Z4V0) is 828 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z4V0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z4V0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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