Keratin-associated protein 19-3 (KRTAP19-3)
Homo sapiens — UniProt Q7Z4W3
Data last refreshed: (UniProt release unknown)
Key facts
Keratin-associated protein 19-3 (KRTAP19-3) is a protein from Homo sapiens identified by UniProt accession Q7Z4W3, 81 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: Q7Z4W3; gene symbol KRTAP19-3.
- Organism: Homo sapiens.
- Length: 81 amino acids.
- Top disease associations (Open Targets): head and neck squamous cell carcinoma, prostate adenocarcinoma and esophageal cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Keratin-associated protein 19-3 |
|---|---|
| UniProt accession | Q7Z4W3 |
| Gene | KRTAP19-3 |
| Organism | Homo sapiens |
| Length | 81 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- head and neck squamous cell carcinoma · score 0.18
- prostate adenocarcinoma · score 0.18
- esophageal cancer · score 0.14
- gastric carcinoma · score 0.01
- rosacea · score 0.00
- atopic eczema · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z4W3-F1 | alphafold | PREDICTED | 51.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z4W3.
Amino-acid sequence (81 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KRTAP19-3?
The strongest Open Targets associations for KRTAP19-3 are head and neck squamous cell carcinoma, prostate adenocarcinoma, esophageal cancer, gastric carcinoma and rosacea.
How long is the KRTAP19-3 protein?
The Homo sapiens KRTAP19-3 protein (UniProt Q7Z4W3) is 81 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z4W3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z4W3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.