Chemokine-like protein TAFA-5 (TAFA5)
Homo sapiens — UniProt Q7Z5A7
Data last refreshed: (UniProt release unknown)
Key facts
Chemokine-like protein TAFA-5 (TAFA5) is a protein from Homo sapiens identified by UniProt accession Q7Z5A7, 132 residues long. MolForge cross-references it against 0 known binders and 89 disease associations.
- UniProt accession: Q7Z5A7; gene symbol TAFA5.
- Organism: Homo sapiens.
- Length: 132 amino acids.
- Top disease associations (Open Targets): body fat percentage, body mass index and high density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Chemokine-like protein TAFA-5 |
|---|---|
| UniProt accession | Q7Z5A7 |
| Gene | TAFA5 |
| Organism | Homo sapiens |
| Length | 132 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (89)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.47
- body mass index · score 0.40
- high density lipoprotein cholesterol measurement · score 0.37
- neurofibrillary tangles measurement · score 0.36
- PHF-tau measurement · score 0.34
- pancreatic carcinoma · score 0.32
- nasopharyngeal neoplasm · score 0.31
- adolescent idiopathic scoliosis · score 0.30
- serum alanine aminotransferase measurement · score 0.29
- sex hormone-binding globulin measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5A7-F1 | alphafold | PREDICTED | 83.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5A7.
Amino-acid sequence (132 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAFA5?
The strongest Open Targets associations for TAFA5 are body fat percentage, body mass index, high density lipoprotein cholesterol measurement, neurofibrillary tangles measurement and PHF-tau measurement.
How long is the TAFA5 protein?
The Homo sapiens TAFA5 protein (UniProt Q7Z5A7) is 132 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5A7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5A7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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