Chemokine-like protein TAFA-3 (TAFA3)
Homo sapiens — UniProt Q7Z5A8
Data last refreshed: (UniProt release unknown)
Key facts
Chemokine-like protein TAFA-3 (TAFA3) is a protein from Homo sapiens identified by UniProt accession Q7Z5A8, 133 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q7Z5A8; gene symbol TAFA3.
- Organism: Homo sapiens.
- Length: 133 amino acids.
- Top disease associations (Open Targets): drug use measurement, glomerular filtration rate and creatinine measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Chemokine-like protein TAFA-3 |
|---|---|
| UniProt accession | Q7Z5A8 |
| Gene | TAFA3 |
| Organism | Homo sapiens |
| Length | 133 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- drug use measurement · score 0.28
- glomerular filtration rate · score 0.24
- creatinine measurement · score 0.11
- Asperger syndrome · score 0.08
- autism · score 0.07
- attention deficit hyperactivity disorder · score 0.07
- Autism · score 0.06
- intellectual disability, autosomal dominant 50 · score 0.06
- trichotillomania · score 0.05
- autism spectrum disorder · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5A8-F1 | alphafold | PREDICTED | 87.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5A8.
Amino-acid sequence (133 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAFA3?
The strongest Open Targets associations for TAFA3 are drug use measurement, glomerular filtration rate, creatinine measurement, Asperger syndrome and autism.
How long is the TAFA3 protein?
The Homo sapiens TAFA3 protein (UniProt Q7Z5A8) is 133 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5A8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5A8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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