Chemokine-like protein TAFA-1 (TAFA1)
Homo sapiens — UniProt Q7Z5A9
Data last refreshed: (UniProt release unknown)
Key facts
Chemokine-like protein TAFA-1 (TAFA1) is a protein from Homo sapiens identified by UniProt accession Q7Z5A9, 133 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q7Z5A9; gene symbol TAFA1.
- Organism: Homo sapiens.
- Length: 133 amino acids.
- Top disease associations (Open Targets): protein measurement, urate measurement and bone density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Chemokine-like protein TAFA-1 |
|---|---|
| UniProt accession | Q7Z5A9 |
| Gene | TAFA1 |
| Organism | Homo sapiens |
| Length | 133 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.40
- urate measurement · score 0.33
- bone density · score 0.33
- refractive error measurement · score 0.32
- neurofibrillary tangles measurement · score 0.30
- monoclonal gammopathy · score 0.29
- adolescent idiopathic scoliosis · score 0.27
- alcohol consumption measurement · score 0.27
- physical activity measurement · score 0.22
- attention deficit hyperactivity disorder · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5A9-F1 | alphafold | PREDICTED | 86.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5A9.
Amino-acid sequence (133 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TAFA1?
The strongest Open Targets associations for TAFA1 are protein measurement, urate measurement, bone density, refractive error measurement and neurofibrillary tangles measurement.
How long is the TAFA1 protein?
The Homo sapiens TAFA1 protein (UniProt Q7Z5A9) is 133 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5A9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5A9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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