NANOG neighbor homeobox (NANOGNB)
Homo sapiens — UniProt Q7Z5D8
Data last refreshed: (UniProt release unknown)
Key facts
NANOG neighbor homeobox (NANOGNB) is a protein from Homo sapiens identified by UniProt accession Q7Z5D8, 188 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q7Z5D8; gene symbol NANOGNB.
- Organism: Homo sapiens.
- Length: 188 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, colorectal adenocarcinoma and atherosclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NANOG neighbor homeobox |
|---|---|
| UniProt accession | Q7Z5D8 |
| Gene | NANOGNB |
| Organism | Homo sapiens |
| Length | 188 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.34
- colorectal adenocarcinoma · score 0.04
- atherosclerosis · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q7Z5D8-F1 | alphafold | PREDICTED | 67.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q7Z5D8.
Amino-acid sequence (188 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NANOGNB?
The strongest Open Targets associations for NANOGNB are neurodegenerative disease, colorectal adenocarcinoma, atherosclerosis and cancer.
How long is the NANOGNB protein?
The Homo sapiens NANOGNB protein (UniProt Q7Z5D8) is 188 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q7Z5D8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q7Z5D8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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